Basic Information
ID: ALA4737441
Type: Binding
Description: Inhibition of human N-terminal GST-tagged CDK2 (1 to 298 residues)/Cyclin A (174 to 432 residues) expressed in Escherichia coli Turner (DE3) cells assessed as reduction in ADP formation using PKTPKKAKKL as substrate by resorufin dye based fluorescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4737441
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 466.54 | 4.35 | 4.35 |
| 340.25 | 3.69 | 3.69 |
| 348.24 | 3.93 | 3.93 |
| 335.21 | 3.02 | 3.02 |
| 368.66 | 4.28 | 4.28 |
| 334.22 | 3.62 | 3.62 |
| 296.33 | 3.54 | 3.54 |
| 334.22 | 3.62 | 3.62 |
| 395.48 | 3.70 | 3.70 |
| 333.23 | 4.23 | 4.23 |
| 270.34 | 2.49 | 2.49 |
| 320.19 | 3.32 | 3.32 |
| 349.23 | 3.21 | 3.21 |
| 336.23 | 3.48 | 3.48 |
| 402.21 | 4.12 | 4.12 |
| 310.20 | 3.15 | 3.15 |
| 379.21 | 3.53 | 3.53 |
| 348.24 | 3.87 | 3.87 |
| 285.35 | 2.88 | 2.88 |
| 449.31 | 3.13 | 3.13 |
| 363.49 | 5.02 | 5.02 |
| 402.21 | 4.64 | 4.64 |
| 289.77 | 3.47 | 3.47 |
| 442.29 | 3.39 | 3.39 |
| 382.26 | 4.38 | 4.38 |
| 298.39 | 2.79 | 2.79 |
| 271.32 | 2.22 | 2.22 |
| 255.32 | 2.73 | 2.73 |
| 427.32 | 3.00 | 3.00 |
| 335.20 | 3.02 | 3.02 |
| 391.27 | 3.58 | 3.58 |
| 320.19 | 3.23 | 3.23 |
| 348.24 | 3.93 | 3.93 |
| 270.34 | 1.89 | 1.89 |
| 306.16 | 2.99 | 2.99 |
| 364.24 | 3.63 | 3.63 |
| 349.23 | 3.62 | 3.62 |
| 269.35 | 3.29 | 3.29 |
| 335.20 | 3.02 | 3.02 |
| 273.31 | 3.20 | 3.20 |
| 376.30 | 4.51 | 4.51 |
| 349.23 | 2.78 | 2.78 |
| 383.29 | 5.38 | 5.38 |
| 369.65 | 3.67 | 3.67 |
| 428.31 | 2.24 | 2.24 |
| 348.24 | 3.41 | 3.41 |
| 390.31 | 4.84 | 4.84 |
| 270.34 | 2.19 | 2.19 |
| 241.29 | 2.42 | 2.42 |
| 402.21 | 4.64 | 4.64 |