Basic Information
ID: ALA4737518
Type: Functional
Description: Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: OVCAR-5
Target: Relaxin receptor 1(ALA1293316)
Document: ALA4732190
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4737518
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 2884.46 | ||
| 3196.87 | ||
| 3056.69 | ||
| 3300.88 | ||
| 3293.92 | ||
| 4897.94 | ||
| 4491.46 | ||
| 3414.05 | ||
| 3328.94 | ||
| 3483.16 | ||
| 3153.80 | ||
| 4165.95 | ||
| 3084.74 | ||
| 5880.01 | ||
| 2829.33 | ||
| 3426.10 | ||
| 3167.87 | ||
| 3357.00 | ||
| 3042.65 | ||
| 2786.26 | ||
| 3258.80 | ||
| 4868.90 | ||
| 3342.97 | ||
| 3413.02 | ||
| 3384.96 | ||
| 3123.70 | ||
| 3028.63 | ||
| 2768.22 | ||
| 2856.40 | ||
| 3070.71 | ||
| 5417.58 | ||
| 2868.34 | ||
| 3315.90 | ||
| 3210.94 | ||
| 3098.77 | ||
| 4066.82 | ||
| 4882.93 | ||
| 4463.41 | ||
| 3511.16 | ||
| 4194.01 | ||
| 3443.26 | ||
| 3140.80 |