Basic Information
ID: ALA4737687
Type: Binding
Description: Inhibition of recombinant human HDAC1 using Ac-LGK(Ac)-AMC as substrate preincubated for 30 mins followed by substrate addition and measured after 90 mins by fluorescence based assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Histone deacetylase 1(ALA325)
Document: ALA4732198
Inhibition of recombinant human HDAC1 using Ac-LGK(Ac)-AMC as substrate preincubated for 30 mins followed by substrate addition and measured after 90 mins by fluorescence based assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4737687
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 264.32 | 2.47 | 2.47 |
| 721.88 | 8.62 | 8.62 |
| 312.37 | 3.18 | 3.18 |
| 342.39 | 2.58 | 2.58 |
| 370.45 | 2.81 | 2.81 |
| 390.40 | 3.10 | 3.10 |
| 354.36 | 1.94 | 1.94 |
| 372.38 | 3.27 | 3.27 |
| 352.39 | 2.74 | 2.74 |
| 456.42 | 5.12 | 5.12 |
| 364.38 | 3.54 | 3.54 |
| 396.40 | 2.44 | 2.44 |
| 352.39 | 2.74 | 2.74 |
| 388.81 | 2.59 | 2.59 |
| 408.44 | 2.82 | 2.82 |
| 296.28 | 1.60 | 1.60 |
| 352.39 | 2.74 | 2.74 |
| 358.40 | 3.63 | 3.63 |
| 373.37 | 2.66 | 2.66 |
| 324.34 | 2.12 | 2.12 |
| 373.37 | 2.66 | 2.66 |
| 227.26 | 2.78 | 2.78 |
| 390.37 | 3.41 | 3.41 |