Basic Information
ID: ALA4737688
Type: ADME
Description: Metabolic stability in Sprague-Dawley rat liver microsomes assessed as half life at 5 uM preincubated for 5 mins followed by NADPH addition and measured after 60 mins by LCMS analysis
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA4737688
T1/2
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 454.61 | 5.09 | 5.09 |
| 264.32 | 2.47 | 2.47 |
| 308.33 | 3.61 | 3.61 |
| 372.38 | 3.27 | 3.27 |
| 352.39 | 2.74 | 2.74 |
| 408.44 | 2.82 | 2.82 |
| 358.40 | 3.63 | 3.63 |
| 390.37 | 3.41 | 3.41 |