Basic Information
ID: ALA4737695
Type: Binding
Description: Inhibition of Class 1 histone deacetylase in human THP-1 cells using Ac-LGK(Ac)-AMC as substrate incubated for 3 hrs followed by 50 uM SAHA addition and measured after 1 hr by fluorescence based assay
Organism: Homo sapiens
Cell type: THP-1
Activity Charts
Bioactivity
Activity Types for Assay ALA4737695
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 312.37 | 3.18 | 3.18 |
| 372.38 | 3.27 | 3.27 |
| 456.42 | 5.12 | 5.12 |
| 408.44 | 2.82 | 2.82 |
| 390.37 | 3.41 | 3.41 |