Basic Information
ID: ALA4738044
Type: Functional
Description: Inhibition of polyol pathway in STZ-induced Kunming mouse model of diabetes assessed as decrease in sorbitol level in kidney cortex at 80 mg/kg, po administered daily via gavage for 8 weeks and measured at 6 hrs post-final drug dose by fluorospectrophotometric analysis
Organism: Mus musculus
Strain: Kunming
Activity Charts
Bioactivity
Activity Types for Assay ALA4738044
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 319.41 | 2.92 | 2.92 |
| 129.17 | -1.03 | -1.03 |
| 341.32 | 2.56 | 2.56 |