Assay Report Card

Basic Information

ID: ALA4738046

Type: Functional

Description: Inhibition of polyol pathway in STZ-induced Kunming mouse model of diabetes assessed as decrease in sorbitol level in kidney cortex at 80 mg/kg, po administered QD via gavage for 4 weeks and measured at 6 hrs post-final drug dose by fluorospectrophotometric analysis

Organism: Mus musculus

Strain: Kunming

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
341.322.562.56