Basic Information
ID: ALA4738941
Type: Binding
Description: Inhibition of recombinant human TOPO1 assessed as TOP1-DNA cleavage complexes at 1 uM using 3'-[32-P]-117 labeled bp DNA as substrate incubated for 30 mins by SDS-PAGE analysis relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4738941
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 474.52 | 6.19 | 6.19 |
| 460.50 | 5.80 | 5.80 |
| 476.50 | 5.04 | 5.04 |
| 426.94 | 5.44 | 5.44 |
| 442.94 | 4.67 | 4.67 |
| 456.97 | 4.80 | 4.80 |
| 490.52 | 5.16 | 5.16 |
| 440.97 | 5.83 | 5.83 |