Basic Information
ID: ALA4739046
Type: Binding
Description: Inhibition of 20S immunoproteasome beta 5 chymotrypsin-like activity in human H226 cell using Suc-LLVY-AMC as substrate for 10 mins by fluorescence based assay
Format: BAO_0000221
Organism: Homo sapiens
Cell type: NCI-H226
Target: Proteasome subunit beta type-8(ALA5620)
Document: ALA4732244
Inhibition of 20S immunoproteasome beta 5 chymotrypsin-like activity in human H226 cell using Suc-LLVY-AMC as substrate for 10 mins by fluorescence based assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4739046
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 580.68 | 0.64 | 0.64 |
| 616.72 | 3.78 | 3.78 |
| 628.77 | 4.79 | 4.79 |
| 694.79 | 4.74 | 4.74 |
| 717.87 | 6.43 | 6.43 |
| 709.84 | 5.48 | 5.48 |
| 736.82 | 4.94 | 4.94 |
| 622.81 | 5.16 | 5.16 |
| 645.80 | 5.15 | 5.15 |
| 576.65 | 2.87 | 2.87 |
| 662.79 | 4.95 | 4.95 |
| 670.81 | 5.00 | 5.00 |
| 724.81 | 4.75 | 4.75 |
| 636.83 | 5.11 | 5.11 |
| 670.85 | 6.26 | 6.26 |
| 643.74 | 1.49 | 1.49 |
| 609.72 | 1.30 | 1.30 |
| 634.82 | 5.09 | 5.09 |
| 586.69 | 3.77 | 3.77 |
| 654.81 | 4.61 | 4.61 |
| 582.70 | 3.37 | 3.37 |
| 666.78 | 4.93 | 4.93 |
| 644.81 | 4.18 | 4.18 |
| 616.72 | 3.39 | 3.39 |
| 668.83 | 5.72 | 5.72 |
| 754.84 | 4.76 | 4.76 |
| 645.80 | 5.15 | 5.15 |
| 594.75 | 4.60 | 4.60 |
| 667.81 | 5.28 | 5.28 |
| 636.79 | 4.80 | 4.80 |
| 625.73 | 4.25 | 4.25 |
| 663.78 | 4.34 | 4.34 |
| 745.90 | 4.68 | 4.68 |