Basic Information
ID: ALA4739072
Type: ADME
Description: Prodrug conversion assessed as bovine kidney GGT-mediated active metabolite,(R)-2-Amino-3-[5-(4-trifluoromethyl-phenyl)-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylsulfanyl]-propionic acid formation at 10 uM incubated for 1 hr by LC-MS analysis
Format: BAO_0000221
Organism: Bos taurus
Tissue: Kidney
Target: Unchecked(ALA612545)
Document: ALA4732246
Prodrug conversion assessed as bovine kidney GGT-mediated active metabolite,(R)-2-Amino-3-[5-(4-trifluoromethyl-phenyl)-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylsulfanyl]-propionic acid formation at 10 uM incubated for 1 hr by LC-MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4739072
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 585.64 | 5.68 | 5.68 |