Basic Information
ID: ALA4739194
Type: Binding
Description: Potency index, ratio of LY-2157299 IC50 to test compound IC50 for recombinant human GST-fused ALK5 expressed in baculovirus infected Sf9 cells assessed as incoporation of [33]Pi after 60 mins in presence of [gamma-33P]-ATP by microplate scintillation counter method
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Sf9
Target: TGF-beta receptor type I(ALA4439)
Document: ALA4732251
Potency index, ratio of LY-2157299 IC50 to test compound IC50 for recombinant human GST-fused ALK5 expressed in baculovirus infected Sf9 cells assessed as incoporation of [33]Pi after 60 mins in presence of [gamma-33P]-ATP by microplate scintillation counter method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4739194
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 408.51 | 5.25 | 5.25 |
| 394.48 | 5.24 | 5.24 |
| 380.46 | 4.94 | 4.94 |
| 412.47 | 5.09 | 5.09 |
| 394.48 | 4.95 | 4.95 |
| 394.48 | 5.24 | 5.24 |
| 398.45 | 5.07 | 5.07 |
| 398.45 | 5.07 | 5.07 |
| 408.51 | 5.25 | 5.25 |
| 398.45 | 5.07 | 5.07 |
| 412.47 | 5.09 | 5.09 |
| 408.51 | 5.25 | 5.25 |
| 412.47 | 5.09 | 5.09 |
| 394.48 | 5.24 | 5.24 |