Basic Information
ID: ALA4739198
Type: Binding
Description: Inhibition of 6His/thrombin cleavage site-fused Avi-tagged dephosphorylated MER (unknown origin) (R528 to M999 residues) using Axltide (CKKSRGDYMTMQJG-acid) peptide as substrate preincubated for 30 mins followed by substrate and ATP addition at Km concentration measured after 120 mins by RapidFire LC-MS analysis
Format: BAO_0000357
Organism: Homo sapiens
Target: Proto-oncogene tyrosine-protein kinase MER(ALA5331)
Document: ALA4732252
Inhibition of 6His/thrombin cleavage site-fused Avi-tagged dephosphorylated MER (unknown origin) (R528 to M999 residues) using Axltide (CKKSRGDYMTMQJG-acid) peptide as substrate preincubated for 30 mins followed by substrate and ATP addition at Km concentration measured after 120 mins by RapidFire LC-MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4739198
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 551.55 | 6.35 | 6.35 |
| 464.47 | 2.80 | 2.80 |
| 498.92 | 3.45 | 3.45 |
| 614.65 | 4.55 | 4.55 |
| 592.58 | 5.49 | 5.49 |
| 532.47 | 3.82 | 3.82 |
| 450.54 | 3.73 | 3.73 |
| 494.62 | 3.98 | 3.98 |
| 516.61 | 4.06 | 4.06 |
| 431.92 | 6.02 | 6.02 |
| 415.88 | 5.34 | 5.34 |
| 416.87 | 4.74 | 4.74 |
| 474.56 | 3.68 | 3.68 |
| 359.38 | 3.52 | 3.52 |
| 370.43 | 2.94 | 2.94 |
| 520.68 | 5.78 | 5.78 |
| 478.50 | 3.11 | 3.11 |
| 362.44 | 3.40 | 3.40 |
| 373.42 | 3.39 | 3.39 |
| 359.38 | 3.37 | 3.37 |
| 355.44 | 3.25 | 3.25 |
| 408.77 | 4.09 | 4.09 |
| 389.46 | 4.34 | 4.34 |