Basic Information
ID: ALA4739607
Type: Binding
Description: Inhibition of recombinant human HPK1 expressed in baculovirus infected insect cells using SRKS1 peptide as substrate incubated for 15 mins followed by substrate addition and measured after 3 hrs by TR-FRET assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Mitogen-activated protein kinase kinase kinase kinase 1(ALA5749)
Document: ALA4732267
Inhibition of recombinant human HPK1 expressed in baculovirus infected insect cells using SRKS1 peptide as substrate incubated for 15 mins followed by substrate addition and measured after 3 hrs by TR-FRET assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4739607
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 383.41 | 3.55 | 3.55 |
| 408.46 | 4.84 | 4.84 |
| 416.46 | 4.70 | 4.70 |
| 409.45 | 4.23 | 4.23 |
| 372.43 | 3.99 | 3.99 |
| 427.44 | 4.37 | 4.37 |