Basic Information
ID: ALA4739791
Type: Binding
Description: Inhibition of biotinylated-THZ1 binding to CDK12/CDK13 in human Jurkat cells assessed as reduction in cyclin K pull down at 500 nM preincubated for 6 hrs followed by biotinylated-THZ1 addition by Western blotting based pulldown assay
Organism: Homo sapiens
Cell type: Jurkat
Activity Charts
Bioactivity
Activity Types for Assay ALA4739791
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 442.57 | 5.10 | 5.10 |
| 553.71 | 5.34 | 5.34 |
| 582.80 | 5.49 | 5.49 |
| 624.83 | 5.66 | 5.66 |
| 499.66 | 5.03 | 5.03 |
| 561.76 | 5.11 | 5.11 |
| 505.71 | 4.45 | 4.45 |
| 561.69 | 6.35 | 6.35 |
| 491.68 | 4.02 | 4.02 |
| 525.70 | 5.56 | 5.56 |
| 541.70 | 5.92 | 5.92 |
| 512.70 | 6.65 | 6.65 |
| 525.70 | 5.56 | 5.56 |