Basic Information
ID: ALA4739837
Type: Binding
Description: Inhibition of CDK7 (unknown origin) assessed as reduction in ATP-dependent phosphorylation of ULight-myelin basic protein substrate peptide incubated for 60 mins by LANCE TR-FRET assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Cyclin-dependent kinase 7(ALA3055)
Document: ALA4739718
Inhibition of CDK7 (unknown origin) assessed as reduction in ATP-dependent phosphorylation of ULight-myelin basic protein substrate peptide incubated for 60 mins by LANCE TR-FRET assay: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA4739837
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 500.60 | 3.92 | 3.92 |
| 433.49 | 4.03 | 4.03 |
| 499.62 | 4.52 | 4.52 |
| 441.54 | 4.38 | 4.38 |
| 400.48 | 4.82 | 4.82 |
| 429.52 | 4.45 | 4.45 |
| 338.41 | 2.83 | 2.83 |
| 416.49 | 3.29 | 3.29 |
| 415.50 | 3.89 | 3.89 |
| 414.51 | 4.50 | 4.50 |
| 415.50 | 3.89 | 3.89 |
| 443.55 | 4.84 | 4.84 |
| 339.40 | 2.23 | 2.23 |
| 513.64 | 4.20 | 4.20 |