Basic Information
ID: ALA4742449
Type: Binding
Description: Inhibition of CDK8 in human SW-620 cells assessed as reduction in STAT1 S727 phosphorylation pre-incubated for 1 hr before IFNgamma stimulation for 3 hrs by Western blot analysis
Organism: Homo sapiens
Cell type: SW-620
Activity Charts
Bioactivity
Activity Types for Assay ALA4742449
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 297.36 | 2.74 | 2.74 |
| 311.39 | 3.22 | 3.22 |
| 297.36 | 3.19 | 3.19 |
| 329.38 | 3.17 | 3.17 |
| 289.31 | 2.25 | 2.25 |
| 313.36 | 2.07 | 2.07 |
| 347.85 | 3.22 | 3.22 |
| 394.40 | 2.91 | 2.91 |
| 255.28 | 1.95 | 1.95 |
| 301.32 | 2.39 | 2.39 |
| 377.44 | 3.97 | 3.97 |
| 271.32 | 2.30 | 2.30 |
| 283.33 | 2.68 | 2.68 |
| 325.41 | 3.68 | 3.68 |