Basic Information
ID: ALA4742482
Type: Functional
Description: Inhibition of CDK8 in athymic nude mouse xenografted with human SW-620 cells assessed as reduction in STAT1 S727 phosphorylation 5 mg/kg, po administered as single dose after 4 hrs by Western blot analysis
Format: BAO_0000218
Organism: Mus musculus
Target: Unchecked(ALA612545)
Document: ALA4742387
Inhibition of CDK8 in athymic nude mouse xenografted with human SW-620 cells assessed as reduction in STAT1 S727 phosphorylation 5 mg/kg, po administered as single dose after 4 hrs by Western blot analysis: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA4742482
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 271.32 | 2.30 | 2.30 |