Basic Information
ID: ALA4742484
Type: Binding
Description: Inhibition of CDK2/Cyclin E (unknown origin) using 5-FAM-CDK7tide substrate incubated for 35 mins
Format: BAO_0000223
Organism: Homo sapiens
Target: Cyclin-dependent kinase 2/cyclin E1(ALA1907605)
Document: ALA4742388
Inhibition of CDK2/Cyclin E (unknown origin) using 5-FAM-CDK7tide substrate incubated for 35 mins: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA4742484
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 362.36 | 3.20 | 3.20 |
| 327.82 | 3.44 | 3.44 |
| 319.37 | 2.06 | 2.06 |
| 441.46 | 4.30 | 4.30 |
| 455.49 | 4.52 | 4.52 |
| 353.86 | 3.78 | 3.78 |
| 427.43 | 4.20 | 4.20 |
| 333.44 | 3.67 | 3.67 |
| 403.92 | 4.90 | 4.90 |
| 440.27 | 4.57 | 4.57 |
| 343.82 | 2.41 | 2.41 |
| 353.86 | 3.78 | 3.78 |
| 352.83 | 3.31 | 3.31 |
| 441.46 | 4.21 | 4.21 |
| 335.46 | 3.66 | 3.66 |
| 396.80 | 3.86 | 3.86 |
| 439.46 | 3.21 | 3.21 |
| 419.45 | 3.93 | 3.93 |
| 355.87 | 4.22 | 4.22 |
| 345.81 | 3.58 | 3.58 |
| 369.86 | 3.64 | 3.64 |
| 419.27 | 3.39 | 3.39 |
| 346.80 | 2.98 | 2.98 |
| 385.90 | 3.80 | 3.80 |
| 441.46 | 4.51 | 4.51 |
| 439.45 | 4.26 | 4.26 |
| 335.46 | 3.66 | 3.66 |
| 323.40 | 2.80 | 2.80 |
| 341.85 | 3.75 | 3.75 |
| 427.43 | 4.20 | 4.20 |
| 497.46 | 4.70 | 4.70 |
| 395.82 | 4.46 | 4.46 |
| 325.39 | 3.24 | 3.24 |
| 447.51 | 4.51 | 4.51 |
| 341.85 | 3.69 | 3.69 |
| 341.80 | 2.97 | 2.97 |
| 386.38 | 3.68 | 3.68 |
| 341.85 | 3.69 | 3.69 |
| 361.37 | 3.81 | 3.81 |
| 403.92 | 4.97 | 4.97 |
| 380.35 | 3.34 | 3.34 |
| 389.43 | 4.59 | 4.59 |
| 345.81 | 3.39 | 3.39 |
| 412.93 | 3.28 | 3.28 |
| 317.40 | 2.77 | 2.77 |
| 385.90 | 3.56 | 3.56 |
| 497.46 | 4.70 | 4.70 |
| 341.85 | 3.83 | 3.83 |
| 438.46 | 4.87 | 4.87 |
| 403.92 | 4.84 | 4.84 |
| 380.35 | 3.34 | 3.34 |
| 341.85 | 3.75 | 3.75 |
| 341.85 | 3.75 | 3.75 |
| 441.46 | 4.21 | 4.21 |
| 459.48 | 3.68 | 3.68 |
| 383.93 | 4.81 | 4.81 |
| 369.90 | 4.56 | 4.56 |
| 341.85 | 3.69 | 3.69 |
| 307.40 | 3.10 | 3.10 |
| 473.54 | 5.22 | 5.22 |
| 369.90 | 4.50 | 4.50 |
| 457.50 | 4.74 | 4.74 |
| 439.46 | 3.21 | 3.21 |
| 441.46 | 4.21 | 4.21 |
| 404.37 | 3.82 | 3.82 |
| 363.51 | 4.30 | 4.30 |
| 335.46 | 3.91 | 3.91 |
| 427.43 | 4.20 | 4.20 |
| 328.81 | 2.84 | 2.84 |
| 339.42 | 3.49 | 3.49 |
| 395.82 | 4.46 | 4.46 |
| 322.42 | 2.75 | 2.75 |
| 371.83 | 3.14 | 3.14 |
| 459.52 | 4.83 | 4.83 |
| 363.80 | 3.72 | 3.72 |
| 376.39 | 3.29 | 3.29 |
| 460.99 | 2.68 | 2.68 |
| 328.81 | 2.84 | 2.84 |
| 412.93 | 3.28 | 3.28 |
| 341.85 | 3.83 | 3.83 |
| 341.85 | 3.69 | 3.69 |
| 328.81 | 2.84 | 2.84 |
| 497.46 | 4.70 | 4.70 |
| 328.81 | 2.61 | 2.61 |
| 340.41 | 2.89 | 2.89 |
| 341.85 | 3.83 | 3.83 |
| 418.42 | 3.17 | 3.17 |
| 418.42 | 3.17 | 3.17 |
| 386.38 | 3.68 | 3.68 |
| 467.43 | 4.38 | 4.38 |
| 397.35 | 4.09 | 4.09 |
| 398.34 | 3.48 | 3.48 |
| 473.54 | 5.22 | 5.22 |
| 454.48 | 2.72 | 2.72 |
| 341.85 | 3.78 | 3.78 |
| 372.27 | 3.55 | 3.55 |
| 331.42 | 2.78 | 2.78 |
| 375.40 | 4.12 | 4.12 |
| 321.43 | 3.35 | 3.35 |
| 345.81 | 3.58 | 3.58 |