Basic Information
ID: ALA4742492
Type: Binding
Description: Inhibition of N-terminal GST tagged human DYRK1A expressed in Sf21 cells incubated for 30 mins by ADP-Glo assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Sf21
Target: Dual-specificity tyrosine-phosphorylation regulated kinase 1A(ALA2292)
Document: ALA4742390
Inhibition of N-terminal GST tagged human DYRK1A expressed in Sf21 cells incubated for 30 mins by ADP-Glo assay: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA4742492
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 451.96 | 2.65 | 2.65 |
| 476.94 | 4.06 | 4.06 |
| 399.86 | 3.00 | 3.00 |
| 306.30 | 3.02 | 3.02 |
| 360.39 | 4.18 | 4.18 |
| 480.59 | 5.13 | 5.13 |
| 263.28 | 3.92 | 3.92 |
| 343.43 | 3.71 | 3.71 |
| 387.44 | 2.97 | 2.97 |
| 396.54 | 5.90 | 5.90 |
| 641.22 | 5.62 | 5.62 |
| 481.94 | 2.97 | 2.97 |
| 329.41 | 3.32 | 3.32 |
| 437.48 | 5.24 | 5.24 |
| 424.48 | 5.06 | 5.06 |
| 527.03 | 5.24 | 5.24 |
| 320.33 | 3.28 | 3.28 |
| 393.45 | 4.51 | 4.51 |
| 423.50 | 5.60 | 5.60 |
| 532.02 | 4.17 | 4.17 |
| 335.41 | 5.75 | 5.75 |
| 340.36 | 4.98 | 4.98 |
| 492.58 | 4.94 | 4.94 |
| 275.31 | 3.79 | 3.79 |
| 416.49 | 4.22 | 4.22 |
| 411.44 | 4.65 | 4.65 |
| 500.60 | 3.81 | 3.81 |
| 321.38 | 5.45 | 5.45 |
| 336.40 | 5.15 | 5.15 |
| 372.43 | 4.04 | 4.04 |
| 416.31 | 3.51 | 3.51 |
| 395.42 | 3.95 | 3.95 |
| 332.36 | 3.15 | 3.15 |
| 295.77 | 4.09 | 4.09 |
| 396.43 | 4.85 | 4.85 |
| 340.39 | 4.98 | 4.98 |
| 379.42 | 4.20 | 4.20 |
| 322.37 | 4.84 | 4.84 |
| 394.44 | 3.69 | 3.69 |
| 376.85 | 4.69 | 4.69 |
| 316.19 | 4.43 | 4.43 |
| 245.28 | 3.78 | 3.78 |
| 576.53 | 5.33 | 5.33 |
| 474.50 | 5.30 | 5.30 |
| 302.34 | 3.14 | 3.14 |
| 533.01 | 3.56 | 3.56 |
| 357.46 | 4.28 | 4.28 |
| 397.41 | 4.94 | 4.94 |
| 436.48 | 4.06 | 4.06 |
| 444.50 | 2.93 | 2.93 |
| 279.73 | 4.43 | 4.43 |
| 459.53 | 6.27 | 6.27 |
| 336.78 | 3.79 | 3.79 |
| 454.94 | 3.20 | 3.20 |
| 382.47 | 4.16 | 4.16 |
| 412.88 | 5.36 | 5.36 |
| 454.94 | 3.20 | 3.20 |
| 473.51 | 5.91 | 5.91 |
| 322.37 | 4.84 | 4.84 |
| 397.41 | 4.34 | 4.34 |
| 376.85 | 4.69 | 4.69 |
| 329.28 | 4.68 | 4.68 |
| 410.52 | 4.71 | 4.71 |
| 400.49 | 3.78 | 3.78 |
| 573.06 | 4.69 | 4.69 |
| 357.46 | 4.46 | 4.46 |