Basic Information
ID: ALA4742531
Type: Binding
Description: Inhibition of CDK8/CDK19 assessed as rescue of proliferation of RPS19-deficient erythroid progenitor cells isolated from mouse model of DBA by cell-based phenotypic screening assay relative to control
Format: BAO_0000221
Organism: Mus musculus
Cell type: Erythroid progenitor cell
Target: CDK8/CDK19(ALA4888455)
Document: ALA4742393
Inhibition of CDK8/CDK19 assessed as rescue of proliferation of RPS19-deficient erythroid progenitor cells isolated from mouse model of DBA by cell-based phenotypic screening assay relative to control: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA4742531
ECmax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 236.30 | 1.04 | 1.04 |
| 367.48 | 2.69 | 2.69 |
| 452.58 | 2.32 | 2.32 |
| 421.93 | 3.91 | 3.91 |
| 410.91 | 2.98 | 2.98 |
| 450.55 | 3.70 | 3.70 |
| 414.14 | 3.23 | 3.23 |
| 274.33 | 3.16 | 3.16 |
| 251.31 | 1.43 | 1.43 |
| 339.42 | 3.53 | 3.53 |
| 275.38 | 2.42 | 2.42 |
| 275.25 | 2.30 | 2.30 |