Basic Information
ID: ALA4742550
Type: Binding
Description: Inhibition of CDK12 (unknown origin) using ULight - 4E - BP1( Thr37 / Thr46 ) as substrate preincubated for 60 mins bu LANCE-TR-FRET assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4742550
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 379.46 | 2.93 | 2.93 |
| 348.41 | 2.43 | 2.43 |
| 390.49 | 3.83 | 3.83 |
| 390.49 | 3.83 | 3.83 |
| 391.48 | 3.23 | 3.23 |
| 405.50 | 3.62 | 3.62 |
| 377.45 | 2.84 | 2.84 |
| 406.53 | 4.36 | 4.36 |
| 404.51 | 4.22 | 4.22 |
| 393.49 | 3.32 | 3.32 |
| 391.48 | 3.23 | 3.23 |
| 394.48 | 2.26 | 2.26 |
| 393.49 | 2.86 | 2.86 |
| 403.49 | 3.06 | 3.06 |
| 408.48 | 3.97 | 3.97 |
| 361.41 | 1.72 | 1.72 |
| 391.48 | 3.06 | 3.06 |
| 475.64 | 4.54 | 4.54 |
| 407.52 | 3.30 | 3.30 |
| 389.46 | 2.50 | 2.50 |
| 447.58 | 3.76 | 3.76 |
| 489.62 | 3.53 | 3.53 |
| 390.49 | 3.83 | 3.83 |
| 393.49 | 3.32 | 3.32 |
| 377.45 | 2.67 | 2.67 |
| 377.45 | 2.67 | 2.67 |
| 408.48 | 3.97 | 3.97 |
| 418.54 | 4.47 | 4.47 |
| 419.53 | 3.86 | 3.86 |
| 375.43 | 2.11 | 2.11 |
| 403.49 | 3.06 | 3.06 |
| 363.42 | 2.27 | 2.27 |
| 405.50 | 3.45 | 3.45 |
| 348.41 | 2.43 | 2.43 |
| 391.48 | 3.06 | 3.06 |
| 392.50 | 3.92 | 3.92 |
| 404.51 | 4.27 | 4.27 |