Basic Information
ID: ALA4742558
Type: Binding
Description: Inhibition of N-terminal His-tagged human PARP15 catalytic domain (481 to 678 residues) expressed in Escherichia coli BL21 (DE3) cells up to 100 uM in presence of NAD+ incubated for 2 hrs by M-ELISA plate method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4742558
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 195.22 | 2.68 | 2.68 |
| 122.13 | 0.18 | 0.18 |
| 161.16 | 1.65 | 1.65 |
| 457.48 | 0.19 | 0.19 |
| 135.13 | -0.11 | -0.11 |
| 434.47 | 2.35 | 2.35 |
| 182.25 | 0.87 | 0.87 |
| 312.32 | 3.66 | 3.66 |