Basic Information
ID: ALA4742559
Type: Binding
Description: Dose dependent inhibition of N-terminal His-tagged human PARP14 catalytic domain 161 1611 to 1801 residues) expressed in Escherichia coli BL21 (DE3) cells up to 100 uM in presence of NAD+ incubated for 2 hrs by M-ELISA plate method
Format: BAO_0000219
Organism: Homo sapiens
Target: Poly [ADP-ribose] polymerase 14(ALA2176777)
Document: ALA4742396
Dose dependent inhibition of N-terminal His-tagged human PARP14 catalytic domain 161 1611 to 1801 residues) expressed in Escherichia coli BL21 (DE3) cells up to 100 uM in presence of NAD+ incubated for 2 hrs by M-ELISA plate method: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA4742559
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 195.22 | 2.68 | 2.68 |
| 122.13 | 0.18 | 0.18 |
| 161.16 | 1.65 | 1.65 |
| 457.48 | 0.19 | 0.19 |
| 135.13 | -0.11 | -0.11 |
| 434.47 | 2.35 | 2.35 |
| 182.25 | 0.87 | 0.87 |
| 312.32 | 3.66 | 3.66 |