Basic Information
ID: ALA4742620
Type: Binding
Description: Inhibition of partial length human MKK4 (S84 to D399 residues) expressed in mammalian expression system assessed as residual percent of control binding at 100 nM relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4742620
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 500.48 | 3.98 | 3.98 |
| 484.53 | 4.90 | 4.90 |
| 563.61 | 3.58 | 3.58 |
| 474.46 | 4.42 | 4.42 |
| 468.47 | 3.14 | 3.14 |
| 510.55 | 4.31 | 4.31 |
| 492.94 | 4.79 | 4.79 |
| 507.50 | 2.15 | 2.15 |
| 558.92 | 5.96 | 5.96 |
| 509.88 | 2.60 | 2.60 |
| 524.51 | 3.47 | 3.47 |
| 486.50 | 4.29 | 4.29 |
| 549.58 | 3.24 | 3.24 |
| 484.53 | 4.98 | 4.98 |
| 549.58 | 3.19 | 3.19 |
| 470.50 | 4.59 | 4.59 |
| 494.98 | 5.86 | 5.86 |
| 488.49 | 4.73 | 4.73 |
| 524.51 | 5.12 | 5.12 |
| 526.97 | 4.54 | 4.54 |
| 501.47 | 4.19 | 4.19 |
| 505.93 | 4.96 | 4.96 |
| 470.50 | 4.59 | 4.59 |
| 584.59 | 3.55 | 3.55 |
| 572.56 | 5.91 | 5.91 |
| 553.54 | 3.07 | 3.07 |
| 549.58 | 3.66 | 3.66 |
| 498.56 | 5.41 | 5.41 |
| 508.49 | 1.40 | 1.40 |
| 501.47 | 4.19 | 4.19 |
| 526.45 | 4.09 | 4.09 |
| 490.92 | 4.94 | 4.94 |
| 474.46 | 4.42 | 4.42 |
| 609.63 | 1.92 | 1.92 |
| 490.92 | 4.94 | 4.94 |
| 535.55 | 2.93 | 2.93 |
| 471.49 | 3.87 | 3.87 |
| 443.44 | 3.29 | 3.29 |
| 490.92 | 4.94 | 4.94 |
| 510.98 | 4.87 | 4.87 |
| 499.54 | 4.35 | 4.35 |
| 504.95 | 5.25 | 5.25 |
| 536.54 | 2.05 | 2.05 |
| 535.55 | 2.93 | 2.93 |
| 505.51 | 4.47 | 4.47 |
| 490.92 | 4.94 | 4.94 |
| 525.36 | 5.59 | 5.59 |
| 595.97 | 2.07 | 2.07 |
| 507.50 | 2.15 | 2.15 |
| 570.00 | 3.59 | 3.59 |
| 486.50 | 4.29 | 4.29 |
| 474.90 | 4.03 | 4.03 |
| 577.59 | 3.11 | 3.11 |
| 525.36 | 5.59 | 5.59 |
| 490.92 | 4.94 | 4.94 |
| 499.54 | 4.35 | 4.35 |
| 610.00 | 2.16 | 2.16 |
| 472.47 | 3.99 | 3.99 |
| 516.98 | 5.20 | 5.20 |
| 553.54 | 3.07 | 3.07 |
| 471.49 | 3.87 | 3.87 |
| 573.58 | 2.37 | 2.37 |
| 520.95 | 4.95 | 4.95 |
| 476.94 | 5.30 | 5.30 |
| 524.47 | 5.30 | 5.30 |
| 496.46 | 2.69 | 2.69 |
| 525.36 | 5.59 | 5.59 |
| 549.58 | 3.24 | 3.24 |
| 457.46 | 3.68 | 3.68 |
| 500.48 | 3.98 | 3.98 |
| 512.58 | 5.58 | 5.58 |
| 472.47 | 3.99 | 3.99 |
| 474.46 | 4.42 | 4.42 |
| 524.47 | 5.30 | 5.30 |
| 499.50 | 3.38 | 3.38 |
| 472.47 | 3.99 | 3.99 |
| 471.49 | 3.87 | 3.87 |
| 549.58 | 3.32 | 3.32 |
| 471.45 | 2.60 | 2.60 |
| 486.50 | 4.29 | 4.29 |
| 505.93 | 4.96 | 4.96 |
| 488.49 | 4.73 | 4.73 |
| 442.45 | 3.81 | 3.81 |
| 534.57 | 3.69 | 3.69 |
| 583.60 | 3.72 | 3.72 |
| 470.50 | 4.59 | 4.59 |
| 553.54 | 3.07 | 3.07 |
| 498.56 | 5.41 | 5.41 |
| 520.52 | 4.78 | 4.78 |
| 510.49 | 4.73 | 4.73 |
| 465.87 | 2.90 | 2.90 |
| 505.53 | 3.54 | 3.54 |
| 456.47 | 4.29 | 4.29 |