Assay Report Card

Basic Information

ID: ALA4742623

Type: Binding

Description: Selectivity index, ratio of inhibition of B-raf (unknown origin) to inhibition of partial length human MKK4 (S84 to D399 residues) expressed in mammalian expression system assessed as residual percent of control binding at 100 nM relative to control

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
500.483.983.98
484.534.904.90
563.613.583.58
474.464.424.42
468.473.143.14
510.554.314.31
492.944.794.79
507.502.152.15
558.925.965.96
509.882.602.60
524.513.473.47
486.504.294.29
484.534.984.98
549.583.193.19
470.504.594.59
494.985.865.86
526.974.544.54
501.474.194.19
505.934.964.96
470.504.594.59
584.593.553.55
553.543.073.07
549.583.663.66
508.491.401.40
501.474.194.19
490.924.944.94
474.464.424.42
609.631.921.92
535.552.932.93
471.493.873.87
443.443.293.29
490.924.944.94
510.984.874.87
499.544.354.35
536.542.052.05
505.514.474.47
490.924.944.94
525.365.595.59
570.003.593.59
486.504.294.29
474.904.034.03
577.593.113.11
525.365.595.59
490.924.944.94
499.544.354.35
472.473.993.99
516.985.205.20
553.543.073.07
471.493.873.87
573.582.372.37
520.954.954.95
476.945.305.30
524.475.305.30
525.365.595.59
549.583.243.24
457.463.683.68
500.483.983.98
512.585.585.58
472.473.993.99
474.464.424.42
524.475.305.30
499.503.383.38
472.473.993.99
471.493.873.87
549.583.323.32
486.504.294.29
505.934.964.96
488.494.734.73
442.453.813.81
534.573.693.69
583.603.723.72
470.504.594.59
553.543.073.07
498.565.415.41
465.872.902.90
456.474.294.29