ID: ALA4742623
Type: Binding
Description: Selectivity index, ratio of inhibition of B-raf (unknown origin) to inhibition of partial length human MKK4 (S84 to D399 residues) expressed in mammalian expression system assessed as residual percent of control binding at 100 nM relative to control
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA4742623
Selectivity ratio
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
500.48 | 3.98 | 3.98 |
484.53 | 4.90 | 4.90 |
563.61 | 3.58 | 3.58 |
474.46 | 4.42 | 4.42 |
468.47 | 3.14 | 3.14 |
510.55 | 4.31 | 4.31 |
492.94 | 4.79 | 4.79 |
507.50 | 2.15 | 2.15 |
558.92 | 5.96 | 5.96 |
509.88 | 2.60 | 2.60 |
524.51 | 3.47 | 3.47 |
486.50 | 4.29 | 4.29 |
484.53 | 4.98 | 4.98 |
549.58 | 3.19 | 3.19 |
470.50 | 4.59 | 4.59 |
494.98 | 5.86 | 5.86 |
526.97 | 4.54 | 4.54 |
501.47 | 4.19 | 4.19 |
505.93 | 4.96 | 4.96 |
470.50 | 4.59 | 4.59 |
584.59 | 3.55 | 3.55 |
553.54 | 3.07 | 3.07 |
549.58 | 3.66 | 3.66 |
508.49 | 1.40 | 1.40 |
501.47 | 4.19 | 4.19 |
490.92 | 4.94 | 4.94 |
474.46 | 4.42 | 4.42 |
609.63 | 1.92 | 1.92 |
535.55 | 2.93 | 2.93 |
471.49 | 3.87 | 3.87 |
443.44 | 3.29 | 3.29 |
490.92 | 4.94 | 4.94 |
510.98 | 4.87 | 4.87 |
499.54 | 4.35 | 4.35 |
536.54 | 2.05 | 2.05 |
505.51 | 4.47 | 4.47 |
490.92 | 4.94 | 4.94 |
525.36 | 5.59 | 5.59 |
570.00 | 3.59 | 3.59 |
486.50 | 4.29 | 4.29 |
474.90 | 4.03 | 4.03 |
577.59 | 3.11 | 3.11 |
525.36 | 5.59 | 5.59 |
490.92 | 4.94 | 4.94 |
499.54 | 4.35 | 4.35 |
472.47 | 3.99 | 3.99 |
516.98 | 5.20 | 5.20 |
553.54 | 3.07 | 3.07 |
471.49 | 3.87 | 3.87 |
573.58 | 2.37 | 2.37 |
520.95 | 4.95 | 4.95 |
476.94 | 5.30 | 5.30 |
524.47 | 5.30 | 5.30 |
525.36 | 5.59 | 5.59 |
549.58 | 3.24 | 3.24 |
457.46 | 3.68 | 3.68 |
500.48 | 3.98 | 3.98 |
512.58 | 5.58 | 5.58 |
472.47 | 3.99 | 3.99 |
474.46 | 4.42 | 4.42 |
524.47 | 5.30 | 5.30 |
499.50 | 3.38 | 3.38 |
472.47 | 3.99 | 3.99 |
471.49 | 3.87 | 3.87 |
549.58 | 3.32 | 3.32 |
486.50 | 4.29 | 4.29 |
505.93 | 4.96 | 4.96 |
488.49 | 4.73 | 4.73 |
442.45 | 3.81 | 3.81 |
534.57 | 3.69 | 3.69 |
583.60 | 3.72 | 3.72 |
470.50 | 4.59 | 4.59 |
553.54 | 3.07 | 3.07 |
498.56 | 5.41 | 5.41 |
465.87 | 2.90 | 2.90 |
456.47 | 4.29 | 4.29 |