Basic Information
ID: ALA4742635
Type: Binding
Description: Inhibition of CDK12/cyclin K (unknown origin) assessed as incoporation of [33]Pi using RBER-IRStide as substrate and in presence of [gamma-33P]-ATP measured after 60 mins under thiol free condition by microplate scintillation counter
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4742635
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 446.51 | 2.82 | 2.82 |
| 405.43 | 3.22 | 3.22 |
| 387.44 | 3.08 | 3.08 |
| 401.47 | 3.11 | 3.11 |
| 386.45 | 3.69 | 3.69 |
| 401.47 | 3.39 | 3.39 |
| 389.46 | 3.30 | 3.30 |
| 388.43 | 2.48 | 2.48 |
| 412.45 | 2.95 | 2.95 |
| 465.54 | 2.48 | 2.48 |
| 417.47 | 3.09 | 3.09 |
| 421.89 | 3.73 | 3.73 |
| 405.43 | 3.22 | 3.22 |
| 448.53 | 3.05 | 3.05 |