Basic Information
ID: ALA4742642
Type: Binding
Description: Selectivity index, ratio of inhibition of full length human JNK1 (M1 to Q384 residues) expressed in mammalian expression system assessed as residual percent of control binding at 100 nM relative to control to inhibition of partial length human MKK4 (S84 to D399 residues) expressed in mammalian expression system assessed as residual percent of control binding at 100 nM relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4742642
Selectivity ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 584.63 | 4.69 | 4.69 |
| 595.62 | 4.78 | 4.78 |
| 506.53 | 5.44 | 5.44 |
| 570.60 | 4.30 | 4.30 |
| 556.57 | 3.91 | 3.91 |
| 549.56 | 5.74 | 5.74 |
| 548.57 | 5.14 | 5.14 |
| 521.55 | 5.02 | 5.02 |
| 623.64 | 3.52 | 3.52 |
| 573.59 | 5.22 | 5.22 |
| 463.89 | 5.03 | 5.03 |
| 506.53 | 5.44 | 5.44 |
| 435.84 | 4.25 | 4.25 |
| 521.55 | 5.75 | 5.75 |
| 659.69 | 3.07 | 3.07 |
| 445.90 | 4.89 | 4.89 |
| 539.99 | 6.70 | 6.70 |
| 523.54 | 6.18 | 6.18 |