Basic Information
ID: ALA4765505
Type: Binding
Description: Agonist activity at human TLR8 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB activation by measuring maximal response by quanti-blue SEAP reporter gene-based spectrophotometric method
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4765505
RUmax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 295.81 | 3.33 | 3.33 |
| 279.81 | 3.25 | 3.25 |
| 280.80 | 2.90 | 2.90 |
| 315.85 | 4.48 | 4.48 |
| 279.81 | 3.63 | 3.63 |
| 295.81 | 2.81 | 2.81 |
| 283.78 | 3.46 | 3.46 |
| 308.81 | 2.42 | 2.42 |
| 297.80 | 3.77 | 3.77 |
| 355.87 | 3.35 | 3.35 |
| 293.84 | 3.94 | 3.94 |
| 309.84 | 3.64 | 3.64 |
| 265.79 | 3.32 | 3.32 |
| 284.79 | 2.93 | 2.93 |
| 295.81 | 3.33 | 3.33 |
| 300.23 | 3.98 | 3.98 |
| 309.84 | 3.64 | 3.64 |
| 325.84 | 3.34 | 3.34 |
| 293.84 | 3.44 | 3.44 |
| 333.79 | 4.34 | 4.34 |
| 300.23 | 3.98 | 3.98 |
| 279.81 | 3.63 | 3.63 |
| 293.84 | 3.88 | 3.88 |
| 323.82 | 3.11 | 3.11 |
| 333.79 | 4.34 | 4.34 |
| 293.84 | 3.94 | 3.94 |
| 283.78 | 3.46 | 3.46 |
| 283.78 | 3.46 | 3.46 |
| 341.89 | 4.99 | 4.99 |
| 295.81 | 3.33 | 3.33 |
| 281.79 | 3.03 | 3.03 |
| 279.81 | 3.63 | 3.63 |
| 189.69 | 1.66 | 1.66 |
| 333.79 | 4.34 | 4.34 |
| 266.78 | 2.72 | 2.72 |
| 323.82 | 3.11 | 3.11 |
| 341.89 | 4.99 | 4.99 |
| 293.84 | 3.94 | 3.94 |
| 293.84 | 3.94 | 3.94 |
| 315.85 | 4.48 | 4.48 |
| 300.23 | 3.98 | 3.98 |