Assay Report Card

Basic Information

ID: ALA4765721

Type: Binding

Description: Inhibition of TrkB in mouse MG87 cells transfected with pFA2-Elk plasmid and pFR-luciferase plasmid assessed as reduction in ERK1/ERK2 phosphorylation at 0.01 to 1 uM after 5 mins in presence of BDNF by Western blot analysis

Organism: Mus musculus

Cell type: MG87

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
383.432.332.33
411.482.932.93
397.462.592.59