Inhibition of PI3K p110alpha in mouse embryonic fibroblast cells assessed as reduction in PDGF-induced AKT phosphorylation at S473 residue preincubate...

Basic Information

ID: ALA4765901

Type: Binding

Description: Inhibition of PI3K p110alpha in mouse embryonic fibroblast cells assessed as reduction in PDGF-induced AKT phosphorylation at S473 residue preincubated for 2 hrs followed by PDGF stimulation and measured after 10 mins

Format: BAO_0000221

Organism: Mus musculus

Cell type: MEF

Target: PI3-kinase p110-alpha subunit(ALA2499)

Document: ALA4765230

Inhibition of PI3K p110alpha in mouse embryonic fibroblast cells assessed as reduction in PDGF-induced AKT phosphorylation at S473 residue preincubated for 2 hrs followed by PDGF stimulation and measured after 10 mins: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4765901

EC50

Total(1)

Parent Molecular Weight	ALogP	Polar Surface Area
477.89	2.96	2.96

Parent Molecular Weight

ALogP

Polar Surface Area

477.89

2.96

Inhibition of PI3K p110alpha in mouse embryonic fibroblast cells assessed as reduction in PDGF-induced AKT phosphorylation at S473 residue preincubate...

Basic Information

Activity Charts

Compound Summary