Assay Report Card

Basic Information

ID: ALA4766247

Type: Functional

Description: Invivo inhibition of MEK in SCID mouse xenografted with human MDA-MB-231 cells assessed as reduction in phosphorylation of MEK in tumor tissue at 40 mg/kg, po QD for 21 days by immunohistochemical analysis

Organism: Mus musculus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
548.575.175.17