ID: ALA4766247
Type: Functional
Description: Invivo inhibition of MEK in SCID mouse xenografted with human MDA-MB-231 cells assessed as reduction in phosphorylation of MEK in tumor tissue at 40 mg/kg, po QD for 21 days by immunohistochemical analysis
Organism: Mus musculus
Bioactivity
Activity Types for Assay ALA4766247
Inhibition
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
548.57 | 5.17 | 5.17 |