Basic Information
ID: ALA4766280
Type: Functional
Description: Agonist activity at human recombinant full length GPR40 overexpressed in human HEK293 cells assessed as increase in inositol phosphate accumulation in presence of terbium cryptate-labeled anti IP1/d2-labelled IP1 measured after 120 mins by HTRF assay relative to AMG837
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4766280
Emax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 438.45 | 6.53 | 6.53 |
| 524.64 | 5.31 | 5.31 |
| 491.63 | 6.41 | 6.41 |
| 440.46 | 4.57 | 4.57 |
| 508.66 | 5.83 | 5.83 |
| 521.66 | 6.42 | 6.42 |
| 497.66 | 6.47 | 6.47 |
| 512.68 | 6.17 | 6.17 |
| 471.57 | 5.98 | 5.98 |
| 538.69 | 5.84 | 5.84 |
| 543.11 | 6.48 | 6.48 |
| 509.62 | 6.55 | 6.55 |
| 522.69 | 6.14 | 6.14 |
| 559.63 | 7.43 | 7.43 |
| 499.68 | 6.39 | 6.39 |
| 509.62 | 6.55 | 6.55 |
| 576.66 | 6.85 | 6.85 |
| 498.65 | 5.86 | 5.86 |
| 493.65 | 6.33 | 6.33 |
| 491.63 | 6.41 | 6.41 |
| 481.59 | 6.00 | 6.00 |
| 505.66 | 6.72 | 6.72 |
| 512.68 | 6.17 | 6.17 |
| 488.03 | 6.50 | 6.50 |
| 498.65 | 5.86 | 5.86 |
| 511.69 | 6.78 | 6.78 |
| 570.73 | 7.53 | 7.53 |
| 509.62 | 6.55 | 6.55 |
| 526.08 | 7.06 | 7.06 |
| 523.63 | 5.85 | 5.85 |
| 536.72 | 6.61 | 6.61 |