Basic Information
ID: ALA4766281
Type: Binding
Description: Displacement of [3H]-(S)-2-(6-((2',6'-dimethyl-4'-(3-(methylsulfonyl)propoxy)biphenyl-3-yl)methoxy)-2,3-dihydrobenzofuran-3-yl)acetic acid from human recombinant full-length GPR40 expressed in human HEK293 cell membrane assessed as dissociation constant measured after 2 hrs by radioligand competitive assay
Organism: Homo sapiens
Cell type: HEK293
Subcellular Fraction: Cell membrane
Activity Charts
Bioactivity
Activity Types for Assay ALA4766281
Kd
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 438.45 | 6.53 | 6.53 |
| 524.64 | 5.31 | 5.31 |
| 491.63 | 6.41 | 6.41 |
| 440.46 | 4.57 | 4.57 |
| 508.66 | 5.83 | 5.83 |
| 497.66 | 6.47 | 6.47 |
| 471.57 | 5.98 | 5.98 |
| 499.68 | 6.39 | 6.39 |
| 493.65 | 6.33 | 6.33 |