Assay Report Card

Basic Information

ID: ALA4766310

Type: Binding

Description: Displacement of [3H]-(S)-2-(6-((2',6'-dimethyl-4'-(3-(methylsulfonyl)propoxy)biphenyl-3-yl)methoxy)-2,3-dihydrobenzofuran-3-yl)acetic acid from human recombinant full-length GPR40 expressed in human HEK293 cell membrane assessed as Koff rate measured after 2 hrs by radioligand competitive assay

Organism: Homo sapiens

Cell type: HEK293

Subcellular Fraction: Cell membrane

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
491.636.416.41
471.575.985.98