Assay Report Card

ID: ALA4767151

Type: Functional

Description: Immuno-adjuvant activity in C57BL/6 mouse assessed as antibody response to (2R,8R,11S,14R,20R)-14-(2-amino-2-oxoethyl)-20-((2S,5R,8S,11R,14S,17R,20S,23R,26S)-5,14-bis((1H-imidazol-5-yl)methyl)-36-(4-(22-(4-((6-amino-2-(2-methoxyethoxy)-8-oxo-7H-purin-9(8H)-yl)methyl)phenyl)-3,7,11,15,22-pentaoxo-6-(3-((2S,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)propyl)-10,14-bis(3-((2S,3S,4S,5S,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)propyl)-2,6,10,14,21-pentaazadocosyl)-1H-1,2,3-triazol-1-yl)-23-(3-amino-3-oxopropyl)-29-sec-butyl-26-(hydroxymethyl)-17-isopropyl-2,8,11,20-tetramethyl-4,7,10,13,16,19,22,25,28,31-decaoxo-3,6,9,12,15,18,21,24,27,30-decaazahexatriacontanamido)-17-sec-butyl-11-(2-carboxyethyl)-2-(3-guanidinopropyl)-8-methyl-4,7,10,13,16,19-hexaoxo-3,6,9,12,15,18-hexaazatricosane-1,23-dioic acid by measuring serum IgG levels at 11 .7 nmol, ID at day 0 and day 21 and measured post second dose

Organism: Mus musculus

Strain: C57BL/6