Basic Information
ID: ALA4767466
Type: Binding
Description: Inhibition of recombinant human PAK4 kinase domain (300 to 591 residues) expressed in Escherichia coli BL21 (DE3) assessed as inhibition rate using serine/threonine-20 peptide as substrate at 0.5 uM incubated for 60 mins in presence of ATP by FRET based Z'-LYTE assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4767466
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 466.54 | 4.35 | 4.35 |
| 448.36 | 3.06 | 3.06 |
| 587.30 | 5.28 | 5.28 |
| 570.05 | 4.46 | 4.46 |
| 556.02 | 4.07 | 4.07 |
| 483.96 | 3.93 | 3.93 |
| 546.03 | 5.11 | 5.11 |
| 570.05 | 4.46 | 4.46 |
| 512.01 | 4.71 | 4.71 |
| 469.93 | 3.54 | 3.54 |
| 497.99 | 4.32 | 4.32 |
| 584.08 | 4.85 | 4.85 |
| 526.04 | 5.10 | 5.10 |
| 512.01 | 4.57 | 4.57 |