Basic Information
ID: ALA4767553
Type: Binding
Description: Inhibition of wild type recombinant HIV-1 subtype B BH10 p66/p51 reverse transcriptase heterodimer expressed in Escherichia coli BL21 (DE3) assessed as inhibition of dTTP incorporation on poly(rA)-oligo(dT) template primer duplex at 10 uM preincubated with enzyme for 2 mins followed by incubation with poly(A)-oligo(dT) templates for 2 hrs by flourescence assay method
Format: BAO_0000019
Organism: Human immunodeficiency virus type 1 BH10
Strain: subtype B
Target: Unchecked(ALA612545)
Document: ALA4765246
Inhibition of wild type recombinant HIV-1 subtype B BH10 p66/p51 reverse transcriptase heterodimer expressed in Escherichia coli BL21 (DE3) assessed as inhibition of dTTP incorporation on poly(rA)-oligo(dT) template primer duplex at 10 uM preincubated with enzyme for 2 mins followed by incubation with poly(A)-oligo(dT) templates for 2 hrs by flourescence assay method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4767553
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 266.30 | 2.65 | 2.65 |
| 162.15 | 1.04 | 1.04 |
| 160.18 | 1.64 | 1.64 |
| 236.27 | 2.93 | 2.93 |
| 252.27 | 2.29 | 2.29 |
| 246.27 | 1.83 | 1.83 |
| 288.33 | 1.83 | 1.83 |
| 232.24 | 1.44 | 1.44 |
| 260.29 | 2.22 | 2.22 |
| 218.21 | 0.94 | 0.94 |
| 190.20 | 0.99 | 0.99 |
| 238.67 | 1.60 | 1.60 |
| 202.26 | 2.12 | 2.12 |
| 224.69 | 2.07 | 2.07 |
| 248.28 | 2.24 | 2.24 |
| 224.65 | 1.21 | 1.21 |
| 204.23 | 1.38 | 1.38 |
| 304.39 | 3.65 | 3.65 |
| 234.25 | 1.99 | 1.99 |
| 252.70 | 1.99 | 1.99 |
| 188.23 | 2.05 | 2.05 |
| 294.78 | 3.02 | 3.02 |
| 266.73 | 2.24 | 2.24 |
| 218.26 | 1.77 | 1.77 |
| 280.75 | 2.63 | 2.63 |
| 262.31 | 2.63 | 2.63 |