Basic Information
ID: ALA4767760
Type: Functional
Description: Antiviral activity against VSVG/HIV-1 harboring reverse transcriptase G190A/K103N double mutant infected in human HEK 293T cells assessed as inhibition of virus replication preincubated with cells for 15 mins prior to viral infection and measured at 48 hrs post-infection by luciferase reporter gene assay
Organism: Human immunodeficiency virus 1
Cell type: HEK293T
Activity Charts
Bioactivity
Activity Types for Assay ALA4767760
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 266.30 | 2.65 | 2.65 |
| 315.68 | 4.07 | 4.07 |
| 342.83 | 4.31 | 4.31 |
| 357.84 | 4.10 | 4.10 |
| 343.81 | 3.71 | 3.71 |
| 338.36 | 2.67 | 2.67 |