Basic Information
ID: ALA4767807
Type: Binding
Description: Antagonist activity at human NOD2 expressed in HEK293 cells assessed as reduction in MDP-induced NF-kappaB activation preincubated for 1 hr followed by MDP stimulation and measured after 18 hrs by SEAP reporter gene based spectrophotometric analysis
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4767807
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 287.34 | 2.16 | 2.16 |
| 438.53 | 4.14 | 4.14 |
| 488.61 | 4.03 | 4.03 |
| 475.57 | 3.08 | 3.08 |
| 438.53 | 4.74 | 4.74 |
| 453.55 | 3.46 | 3.46 |
| 439.52 | 3.53 | 3.53 |
| 567.72 | 4.90 | 4.90 |
| 474.59 | 3.68 | 3.68 |
| 424.50 | 4.09 | 4.09 |
| 488.61 | 4.07 | 4.07 |
| 439.52 | 3.53 | 3.53 |
| 452.56 | 4.53 | 4.53 |
| 482.03 | 2.82 | 2.82 |
| 581.74 | 5.25 | 5.25 |
| 424.55 | 4.50 | 4.50 |
| 545.68 | 4.47 | 4.47 |
| 502.64 | 4.42 | 4.42 |
| 425.54 | 3.89 | 3.89 |