Basic Information
ID: ALA4767808
Type: Binding
Description: Selectivity index, ratio of IC50 for antagonist activity at human NOD1 expressed in HEK293 cells assessed as reduction in C12-iEE-DAP induced NF-kappaB activation preincubated for 1 hr followed by C12-iE-DAP stimulation and measured after 18 hrs by SEAP reporter gene based spectrophotometric analysis to IC50 for antagonist activity at human NOD2 cells expressed in HEK293 cells assessed as reduction in MDP induced NF-kappaB activation preincubated for 1 hr followed by MDPA stimulation and measured after 18 hrs by SEAP reporter gene based spectrophotometric analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4767808
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 438.53 | 4.14 | 4.14 |