Assay Report Card

Basic Information

ID: ALA4767813

Type: Binding

Description: Antagonist activity at NOD2 in human THP-1 cells assessed as reduction in MDP-induced IL-8 secretion at 20 uM preincubated for 1 hr followed by MDP stimulation and measured after 20 hrs by ELISA

Organism: Homo sapiens

Cell type: THP-1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
438.534.144.14
567.724.904.90
474.593.683.68
452.564.534.53