Basic Information
ID: ALA4768153
Type: Binding
Description: Potentiator activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o cells assessed as increase in forskolin induced transepithelial short circuit current at 10 to 100 uM by Ussing chamber assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CFBE41o-
Target: Cystic fibrosis transmembrane conductance regulator(ALA4051)
Document: ALA4765267
Potentiator activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o cells assessed as increase in forskolin induced transepithelial short circuit current at 10 to 100 uM by Ussing chamber assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4768153
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 360.76 | 1.45 | 1.45 |
| 254.25 | 0.50 | 0.50 |
| 376.76 | 0.43 | 0.43 |
| 239.24 | 0.91 | 0.91 |
| 308.13 | 2.22 | 2.22 |
| 387.45 | 2.54 | 2.54 |
| 269.27 | 0.08 | 0.08 |
| 270.25 | 0.20 | 0.20 |
| 254.25 | 0.50 | 0.50 |
| 288.70 | 1.15 | 1.15 |