Assay Report Card

Basic Information

ID: ALA4768208

Type: Binding

Description: Inhibition of STEP in serum deprived rat PC-12 cells assessed as increase in NGF-induced ERK1/2 phosphorylation at T202/Y204 pretreated at 20 uM for 2 hrs followed by stimulated with NGF for 5 mins by Western blotting analysis

Organism: Rattus norvegicus

Cell type: PC-12

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
498.966.476.47
358.354.424.42
364.384.684.68
559.877.097.09