Basic Information
ID: ALA4768583
Type: Binding
Description: Inhibition of recombinant human full-length N-terminal GST-fused CDK4 (1 to 303 residues)/GST-tagged CyclinD3 (1 to 292 residues) expressed in baculovirus expression system using ULight-elF4E-binding protein 1 peptide as substrate measured after 30 mins by LANCE assay
Format: BAO_0000019
Organism: Homo sapiens
Target: CDK4/Cyclin D3(ALA3038472)
Document: ALA4765279
Inhibition of recombinant human full-length N-terminal GST-fused CDK4 (1 to 303 residues)/GST-tagged CyclinD3 (1 to 292 residues) expressed in baculovirus expression system using ULight-elF4E-binding protein 1 peptide as substrate measured after 30 mins by LANCE assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4768583
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 447.54 | 2.97 | 2.97 |
| 506.61 | 4.94 | 4.94 |
| 457.58 | 4.24 | 4.24 |
| 348.80 | 4.16 | 4.16 |
| 426.53 | 3.73 | 3.73 |
| 443.56 | 4.07 | 4.07 |
| 393.25 | 4.27 | 4.27 |
| 484.61 | 4.24 | 4.24 |
| 472.60 | 4.19 | 4.19 |
| 469.59 | 4.60 | 4.60 |
| 477.57 | 4.61 | 4.61 |
| 472.55 | 3.10 | 3.10 |
| 444.54 | 3.46 | 3.46 |
| 486.62 | 3.97 | 3.97 |
| 485.59 | 4.67 | 4.67 |
| 415.50 | 3.25 | 3.25 |
| 483.62 | 4.99 | 4.99 |
| 238.25 | 1.35 | 1.35 |
| 473.54 | 3.12 | 3.12 |
| 399.46 | 3.35 | 3.35 |
| 415.50 | 3.70 | 3.70 |
| 458.57 | 3.46 | 3.46 |
| 498.59 | 3.18 | 3.18 |
| 314.35 | 3.51 | 3.51 |
| 472.60 | 3.63 | 3.63 |
| 398.47 | 2.92 | 2.92 |