Basic Information
ID: ALA4768593
Type: ADME
Description: Inhibition of CYP2D6 in human liver microsomes at 10 uM measured after 20 mins in presence of NADPH by LC-MS/MS analysis relative to control
Format: BAO_0000251
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsomes
Target: Cytochrome P450 2D6(ALA289)
Document: ALA4765279
Inhibition of CYP2D6 in human liver microsomes at 10 uM measured after 20 mins in presence of NADPH by LC-MS/MS analysis relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4768593
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 457.58 | 4.24 | 4.24 |
| 443.56 | 4.07 | 4.07 |