Inhibition of CYP3A4 in human liver microsomes at 10 uM measured after 20 mins in presence of NADPH by LC-MS/MS analysis relative to control

Basic Information

ID: ALA4768594

Type: ADME

Description: Inhibition of CYP3A4 in human liver microsomes at 10 uM measured after 20 mins in presence of NADPH by LC-MS/MS analysis relative to control

Format: BAO_0000251

Organism: Homo sapiens

Tissue: Liver

Subcellular Fraction: Microsomes

Target:  Cytochrome P450 3A4(ALA340)

Document:  ALA4765279

Inhibition of CYP3A4 in human liver microsomes at 10 uM measured after 20 mins in presence of NADPH by LC-MS/MS analysis relative to control: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
457.584.244.24
443.564.074.07