ID: ALA4768594
Type: ADME
Description: Inhibition of CYP3A4 in human liver microsomes at 10 uM measured after 20 mins in presence of NADPH by LC-MS/MS analysis relative to control
Format: BAO_0000251
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsomes
Target: Cytochrome P450 3A4(ALA340)
Document: ALA4765279
Inhibition of CYP3A4 in human liver microsomes at 10 uM measured after 20 mins in presence of NADPH by LC-MS/MS analysis relative to control: 1
Bioactivity
Activity Types for Assay ALA4768594
Inhibition
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
457.58 | 4.24 | 4.24 |
443.56 | 4.07 | 4.07 |