Inhibition of recombinant human HER2 (676 to end residues) assessed as residual activity at 1 uM using poly(Glu, Tyr) 4:1 as substrate incubated for 4...

Basic Information

ID: ALA4769248

Type: Binding

Description: Inhibition of recombinant human HER2 (676 to end residues) assessed as residual activity at 1 uM using poly(Glu, Tyr) 4:1 as substrate incubated for 40 mins by [gamma-33P]-ATP scintillation counting based radiometry assay relative to control

Format: BAO_0000357

Organism: Homo sapiens

Target:  Receptor protein-tyrosine kinase erbB-2(ALA1824)

Document:  ALA4765301

Inhibition of recombinant human HER2 (676 to end residues) assessed as residual activity at 1 uM using poly(Glu, Tyr) 4:1 as substrate incubated for 40 mins by [gamma-33P]-ATP scintillation counting based radiometry assay relative to control: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
459.584.144.14
494.625.555.55
448.554.334.33
539.624.944.94
445.553.793.79
556.684.804.80
424.574.234.23
450.594.464.46
555.695.415.41
486.655.415.41
540.614.334.33
539.624.944.94
523.713.933.93
508.655.895.89
459.584.144.14
410.553.843.84
445.553.793.79
445.553.793.79
472.625.055.05
474.594.204.20
434.533.993.99
540.614.334.33
539.624.944.94
458.594.714.71
574.764.344.34
568.636.076.07
555.695.415.41
535.745.125.12
590.824.814.81
464.624.804.80
519.684.664.66
396.523.503.50
459.584.144.14
556.684.804.80
555.695.415.41