Assay Report Card

Basic Information

ID: ALA4769570

Type: Binding

Description: Inhibition of PI3Kalpha in human T47D cells assessed as inhibition of insulin-stimulated Akt phosphorylation at Ser473 residue at 3 uM preincubated for 2 hrs followed by incubation with insulin for 2 hrs by western blot analysis relative to control

Organism: Homo sapiens

Cell type: T47D

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
380.412.922.92
505.995.215.21