Basic Information
ID: ALA4769572
Type: Binding
Description: Inhibition of PI3Kalpha in human T47D cells assessed as inhibition of insulin-stimulated Akt phosphorylation at Ser473 residue at 0.3 uM preincubated for 2 hrs followed by incubation with insulin for 2 hrs by western blot analysis relative to control
Organism: Homo sapiens
Cell type: T47D
Activity Charts
Bioactivity
Activity Types for Assay ALA4769572
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 380.41 | 2.92 | 2.92 |
| 505.99 | 5.21 | 5.21 |