Basic Information
ID: ALA4770542
Type: ADME
Description: Metabolic stability in rat liver microsomes assessed as apparent intrinsic clearance at 10 uM preincubated for 10 mins followed by NADPH addition and measured after 30 mins
Format: BAO_0000251
Organism: Rattus norvegicus
Tissue: Liver
Subcellular Fraction: Microsome
Target: ADMET(ALA612558)
Document: ALA4765335
Metabolic stability in rat liver microsomes assessed as apparent intrinsic clearance at 10 uM preincubated for 10 mins followed by NADPH addition and measured after 30 mins: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4770542
CL
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 469.00 | 6.14 | 6.14 |
| 420.51 | 2.71 | 2.71 |
| 531.70 | 7.72 | 7.72 |
| 533.67 | 6.30 | 6.30 |
| 532.69 | 6.66 | 6.66 |
| 470.97 | 4.72 | 4.72 |
| 535.04 | 4.99 | 4.99 |
| 503.60 | 3.64 | 3.64 |
| 534.66 | 5.24 | 5.24 |
| 501.63 | 5.06 | 5.06 |